By José Marín-García; Michael J Goldenthal; Gordon W Moe
Read or Download Aging and the heart : a post-genomic view PDF
Similar cardiovascular books
Regardless of extraordinary healing achievements in drugs, cardiovascular illnesses stay the foremost reason behind dying within the new millennium. The heart problems continuum begins with possibility elements reminiscent of high blood pressure, diabetes mellitus and lipid problems, resulting in coronary artery sickness or left ventricular hypertrophy.
Das "Echokardiographie-Handbuch" entwickelt den kurzen Weg von den pathophysiologischen Grundlagen zur echokardiographischen Befundung. Der Leser wird durch eine intestine gegliederte Darstellung rasch in die Lage versetzt, eine echokardiographische Untersuchung selbstständig durchzuführen. Die kardiologischen Konsequenzen aus den erhobenen Daten werden besprochen.
This significant other to Braunwald's middle ailment equips you with all of ultra-modern leading healing guidance and administration ideas for the entire diversity of center affliction sufferers. It displays the latest criteria for drug administration in addition to the newest in new applied sciences. Reorganized to reflect your altering perform, every one cardiovascular-problem-based part bargains a bankruptcy on pharmacologic therapy (with no less than pathophysiology).
This publication offers the main updated assurance of the mixed use of imaging modalities with a view to gather very important sensible and morphological info on heart problems and increase sickness detection. the new advancements in PET/MRI, cardiac CT, PET/CT and SPECT/CT and their influence on medical perform are defined and exact awareness can also be dedicated to imaging parameters and protocols to be used in perform and examine.
- An Introduction to Cardiovascular Physiology
- Resuscitation of Patients in Ventricular Fibrillation from the Perspective of Emergency Medical Services
- Grossman's Cardiac Catheterization, Angiography, and Intervention
- Atlas of Cardiovascular Magnetic Resonance Imaging: Expert Consult - Online and Print: Imaging Companion to Braunwald's Heart Disease, 1e
- Ventricular Function and Blood Flow in Congenital Heart Disease
Additional resources for Aging and the heart : a post-genomic view
Drosophila dFOXO controls life span and regulates insulin signalling in brain and fat body. Nature 2004;429:562–566 44. Kaeberlein M, McVey M, Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev 1999;13:2570–2580 45. Sinclair D, Guarente L. Extrachromosomal rDNA circles – a cause of aging in yeast. Cell 1997;91:1033–1042 46. Tissenbaum HA, Guarente L. Increased dosage of a sir-2 gene extends life span in C. elegans.
Fungal Genet Biol 1999;27:26–35 38. Lorin S, Dufour A, Sainsard A. Mitochondrial metabolism and aging in the filamentous fungus Podospora anserina. Biochim Biophys Acta 2006:1757:604–610 28 Post-Genomic View of Aging: Definitions, Theories and Observations 39. Morrow G, Samson M, Michaud S, Tanguay RM. Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress. FASEB J 2004;18:598–599 40. Morrow G, Battistini S, Zhang P, Tanguay RM.
Also shown are antioxidant factors in peroxisomes (catalase), mitochondria (GPx, GSH and MnSOD) and in the cytosol (CuSOD), which function to scavenge ROS and reduce their impact. increased life span . This can be explained if radiation exposure produces a stable activation of cellular defenses . Similarly caloric restriction (CR), which can be viewed as another form of moderate stress conditioning, can prolong the life span of almost every organism in which it has been used. Considerable evidence has shown that dietary restriction including reduction in caloric intake impacts cellular metabolism including redox remodeling, reducing ROS production and upregulating antioxidant defenses .